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Table 2 Types of Preterm Birth and Risk Factors

From: Born Too Soon: The global epidemiology of 15 million preterm births

Type:

Risk Factors:

Examples:

Interventions:*

Spontaneous preterm birth:

Age at pregnancy and pregnancy spacing

Adolescent pregnancy, advanced maternal age, or short inter-pregnancy interval

Preconception care, including encouraging family planning beginning in adolescence and continuing between pregnancies

 

Multiple pregnancy

Increased rates of twin and higher order pregnancies with assisted reproduction

Introduction and monitoring of policies for best practice in assisted reproduction

 

Infection

Urinary tract infections, asymptomatic bactiuria, malaria, HIV, syphilis, chorioamnionitis, bacterial vaginosis

Sexual health programs aimed at prevention and treatment of infections prior to pregnancy. Specific interventions to prevent infections and mechanisms for early detection and treatment of infections occurring during pregnancy.

 

Underlying maternal chronic medical conditions

Diabetes, hypertension, anaemia, asthma, thyroid disease

Improve control prior to conception and throughout pregnancy

 

Nutritional

Undernutrition, micronutrient deficiencies

See following papers in supplement [66, 67]

 

Lifestyle/work related

Smoking, excess alcohol consumption, recreational drug use, excess physical work/activity

Behavior and community interventions targeting all women of childbearing age in general and for pregnant women in particular through antenatal care with early detection and treatment of pregnancy complications

 

Maternal psychological health

Depression, violence against women

See following papers in supplement [66, 67]

 

Genetic and other

Genetic risk, e.g., family history Cervical incompetence Intra-uterine growth restriction Congenital abnormality

See following papers in supplement [66, 67]

Provider-initiated preterm birth:

Medical induction or cesarean birth for:

Prior classical cesarean section, Placenta accrete.

In addition to the above: Programs and policies to reduce the practice of non-medically indicated induction of labor or cesarean birth

 

obstetric indication Fetal indication

Other - Not medically indicated

There is an overlap for indicated provider-initiated preterm birth with the risk factors for spontaneous preterm birth

 
  1. *Broad categories of possible interventions are listed here. They provide examples of possible interventions and not all the risk factors given in the examples are amenable to these interventions.