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Table 5 Prevalence of BD in Monchegorsk, stratified by time-periods

From: Prevalence of birth defects in an Arctic Russian setting from 1973 to 2011: a register-based study

Prevalence1

73-82

83-92

93-02

03-11

p-value for trend

Total perinatal prevalence

23.5

40.5

38.7

46.3

<0.0001

(20.4-26.6)

(36.7-44.3)

(33.7-43.7)

(40.7-51.9)

Prevalence by EUROCAT guideline

17.7

26.0

31.1

37.8

<0.0001

(15.0-20.4)

(22.9-29.1)

(26.6-35.6)

(32.7-42.9)

Mandatory BD (22 forms)

4.8

7.6

11.3

6.9

0.11

(3.4-6.3)

(5.9-9.3)

(8.6-14.1)

(4.7-9.1)

  1. 1Per 1000 newborns (LB plus SB) with the 95% CI presented in parentheses.