From: Prevalence of birth defects in an Arctic Russian setting from 1973 to 2011: a register-based study
Group of birth defect | 73-82 | 83-92 | 93-02 | 03-11 | p-value for trend |
---|---|---|---|---|---|
Congenital malformations of the nervous system | 0.8 | 2.0 | 2.8 | 1.9 | 0.04 |
(0.2-1.3) | (1.2-2.9) | (1.4-4.2) | (0.7-3.9) | ||
Congenital malformations of eye, ear, face and neck | 0.2 | 0.3 | 1.1 | 1.1 | 0.02 |
(0–0.5) | (0–0.6) | (0.2-1.9) | (0.2-2.0) | ||
Congenital malformations of the circulatory system | 2.4 | 1.9 | 2.8 | 1.3 | 0.37 |
(1.4-3.4) | (1.1-2.8) | (1.4-4.2) | (0.3-2.3) | ||
Congenital malformations of the respiratory system | 1.3 | 0.6 | 1.4 | 0.6 | 0.38 |
(0.6-2.1) | (0.1-1.1) | (0.4-2.4) | (0–1.2) | ||
Cleft lip and cleft palate | 1.3 | 0.7 | 2.1 | 1.9 | 0.46 |
(0.6-2.1) | (0.2-1.2) | (0.9-3.3) | (0.3-2.3) | ||
Other congenital malformations of the digestive system | 1.4 | 1.3 | 0.7 | 1.1 | 0.37 |
(0.7-2.2) | (0.6-2.0) | (0–1.4) | (0.2-2.0) | ||
Congenital malformations of genital organs | 1.8 | 4.6 | 4.9 | 3.9 | 0.02 |
(0.9-2.6) | (3.3-5.9) | (3.1-6.8) | (2.2-5.6) | ||
Congenital malformations of the urinary system | 0.2 | 0.4 | 4.4 | 19.1 | <0.0001 |
(0–0.5) | (0–0.8) | (2.7-6.1) | (15.4-22.7) | ||
Congenital malformations and deformations of the musculoskeletal system | 8.3 | 17.3 | 13.6 | 10.2 | 0.39 |
(6.5-10.2) | (14.8-19.8) | (10.6-16.6) | (7.5-12.9) | ||
Other congenital malformations, excluding multiple | 2.4 | 6.6 | 1.4 | 2.2 | 0.14 |
(1.4-3.4) | (5.0-8.2) | (0.4-2.4) | (1.0-3.5) | ||
Chromosomal abnormalities, not elsewhere classified | 1.0 | 0.6 | 0.5 | 0.7 | 0.51 |
(0.3-1.6) | (0.1-1.1) | (0–1.1) | (0–1.5) | ||
Multiple congenital malformation, not classified | 2.3 | 4.2 | 2.8 | 3.0 | 0.71 |
(1.3-3.3) | (2.9-5.4) | (1.4-4.2) | (1.5-4.4) |