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Fig. 1 | Reproductive Health

Fig. 1

From: Changes in receptivity epithelial cell markers of endometrium after ovarian stimulation treatments: its role during implantation window

Fig. 1

Endometrial expression of epithelial receptivity markers. Immunohistochemistry for GdA (a to g) and LIF (h to n). Positive staining was observed in glandular epithelium (brown and arrows), which was counterstained with Hematoxylin (blue nuclei). (a) Human mid-secretory endometrium and (h) human lung tissue was used as the positive control. (b and i) Human endometrium with no primary antibody served as the negative control. (c and j) Ovulatory women. (d and k) untreated anovulatory infertile women. (e and l) CC-treated anovulatory infertile women. (f and m) rFSH-treated women. (g) Optical density analysis of GdA in the glandular epithelium showed a significantly lower expression (*P < 0.05) in CC- and rFSH-treated groups compared with ovulatory and untreated infertile women. (n) Optical density analysis for LIF showed no significant differences between groups. GE = glandular epithelium; LE = luminal epithelium; S = stroma; OP = ovulatory women; CC = anovulatory infertile patients treated with clomiphene citrate; rFSH = anovulatory infertile patients treated with the recombinant follicle stimulating hormone; UI = anovulatory untreated patients. (Bar = 100 μm)

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