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Table 4 Associations between urinary phthalate metabolite concentrations and serum INHB1 in multivariable linear models (n = 404)

From: Urinary phthalate metabolites in relation to serum anti-Müllerian hormone and inhibin B levels among women from a fertility center: a retrospective analysis

Metabolite

Model 14

Model 25

Percent change6 (95% CI)

Percent change6 (95% CI)

MMP2

  

 17 (< 5.18)

Ref

Ref

 2 (5.18–12.21)

−2.47 (− 17.72, 15.49)

− 0.30 (− 15.80, 17.94)

 3 (12.21–25.78)

−1.00 (− 16.72, 17.70)

3.15 (− 13.24, 22.75)

 4 (> 25.78)

4.71 (− 11.75, 24.23)

5.23 (− 11.13, 24.73)

MEP2

  

 17 (< 6.02)

Ref

Ref

 2 (6.02–12.80)

−4.40 (− 19.83, 14.00)

− 3.92 (− 19.27, 14.34)

 3 (12.80–33.98)

3.36 (− 13.50, 23.49)

1.82 (− 14.62, 21.41)

 4 (> 33.98)

0.50 (− 16.31, 20.56)

− 0.80 (− 17.22, 18.89)

MBP2

  

 17 (< 73.85)

Ref

Ref

 2 (73.85–184.55)

− 9.79 (− 24.19, 7.47)

−11.84 (− 25.84, 4.81)

 3 (184.55–342.12)

− 16.56 (− 30.65, 0.50)

−18.62 (− 32.23, − 2.18)

 4 (> 342.12)

− 14.02 (− 30.16, 5.87)

−15.46 (− 31.20, 3.87)

MBzP2

  

 17 (< 0.035)

Ref

Ref

 2 (0.035–0.102)

−9.43 (− 23.59, 7.36)

− 9.34 (− 23.43, 7.25)

 3 (0.102–0.27)

− 7.78 (− 23.28, 10.96)

−5.45 (− 21.34, 13.54)

 4 (> 0.27)

3.46 (− 13.84, 24.23)

4.39 (− 12.89, 25.23)

MEHP2

  

 17 (< 6.95)

Ref

Ref

 2 (6.95–17.21)

− 13.32 (− 26.80, 2.53)

− 13.58 (− 26.88, 2.12)

 3 (17.21–36.01)

− 12.89 (− 26.95, 3.87)

−14.02 (− 27.75, 2.33)

 4 (> 36.01)

− 17.55 (− 31.34, − 0.90)

− 18.29 (− 31.89, − 1.98)*

MEHHP2

  

 17 (< 10.94)

Ref

Ref

 2 (10.94–19.09)

−7.78 (− 23.05, 10.52)

− 7.41 (− 22.59, 10.74)

 3 (19.09–34.68)

1.61 (−16.56, 23.61)

1.71 (− 16.31, 23.61)

 4 (> 34.68)

− 3.63 (− 21.42, 18.18)

−5.07 (− 22.43, 16.18)

MEOHP2

  

 17 (< 7.41)

Ref

Ref

 2 (7.41–15.34)

− 22.74 (− 35.14, − 7.87)

−23.74 (− 35.85, − 9.24)

 3 (15.34–27.72)

− 19.59 (− 33.17, − 3.25)

−19.91 (− 33.30, − 3.82)

 4 (> 27.72)

−17.80 (− 32.56, 0.20)

− 20.23 (− 34.43, − 2.96)

∑DEHP2

  

 17 (< 0.10)

Ref

Ref

 2 (0.10–0.19)

−9.43 (− 23.97, 7.90)

−11.04 (− 25.25, 5.87)

 3 (0.19–0.35)

−13.58 (− 28.18, 3.87)

− 14.10 (− 28.39, 3.15)

 4 (> 0.35)

−12.10 (− 27.75, 6.82)

− 13.76 (− 28.97, 4.71)

MOP3

−2.76 (− 14.62, 10.74)

−1.78 (− 13.67, 11.74)

  1. *Tests for linear trend with P-value < 0.05. Statistically significant results comparing a specific category to the reference are bolded
  2. 1Serum INHB levels were natural logarithm transformed
  3. 2Phthalate metabolite concentrations were categorized into quartiles
  4. 3Dichotomous variable based on above/below limits of detection
  5. 4Model 1 was adjusted for age, BMI and creatinine
  6. 5Model 2 was adjusted for age, BMI, creatinine and PCO/PCOS diagnosis (yes or no)
  7. 6Percent change and 95% CI were calculated as follows: [exp (β)-1]*100
  8. 7Reference category
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Reproductive Health

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