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Table 2 Stratified analyses for PCOS and risk of NAFLD

From: A potential link between polycystic ovary syndrome and non-alcoholic fatty liver disease: an update meta-analysis

  

Studies, n

OR a (95% CI)

I2 (%)

Heterogeneity

     

0.40

Diagnostic criteria for PCOS

Rotterdam criteria

13

2.19 (1.88–2.55)

13.2

0.312

 

no Rotterdam criteriab

3

3.31 (1.89–5.82)

0

0.446

Diagnosis for NAFLD

ultrasonography

15

2.29 (1.96–2.67)

12.9

0.309

BMI

Non-obese subjectsc

3

2.07 (1.12–3.85)

0

0.680

 

obese subjects

5

3.01 (1.88–4.82)

0

0.705

Androgen levels

HA

3

3.31 (2.58–4.24)

0

0.543

 

Non- HA

3

1.46 (0.55–3.87)

83.3

0.002

Geographic region

Asia-Pacific

5

2.32 (1.89–2.84)

36.4

0.178

 

America

5

2.96 (1.93–4.55)

0

0.760

 

Europe

7

2.00 (1.58–2.52)

3.9

0.396

  1. aOR comparing groups of PCOS to the matched controls with regard to the risk of NAFLD
  2. bincluding NIH criteria or Androgen Excess Society criteria
  3. cdefined as BMI < 25 kg/m2