Table 4 Comparative analysis of children exposed to tenofovir and zidovudine at CAISM/UNICAMP from 2000 to 2015
Variables | TDF | AZT | p* | RR | CI 95% | ||
|---|---|---|---|---|---|---|---|
n | % | n | % | ||||
Gestational age (Capurro) | 0.8962 | ||||||
<37 weeks | 8 | 21.1 | 153 | 22 | 0.95 | 0.44–2.03 | |
>=37 weeks | 30 | 78.9 | 544 | 78 | 1 | ||
Birth weight | 0.5221 | ||||||
<2500 g | 7 | 17.9 | 158 | 22.3 | 0.77 | 0.35–1.72 | |
>=2500 g | 32 | 82.1 | 550 | 77.7 | 1 | ||
Weight adequacy for GA | 0.3722 | 1 | |||||
Adequate for GA | 28 | 73.7 | 563 | 80.3 | 1.29 | 0.60–2.76 | |
Small for GA | 8 | 21.1 | 123 | 17.5 | 2.48 | 0.64–9.59 | |
Large for GA | 2 | 5.3 | 15 | 2.1 | |||
5th minute Apgar | 1.000** | ||||||
<7 | 0 | 0 | 5 | 0.7 | |||
>=7 | 38 | 100 | 701 | 99.3 | |||
Neonatal disease | 0.0056 | ||||||
Yes | 18 | 46.2 | 179 | 25.9 | 2.32 | 1.26–4.26 | |
No | 21 | 53.8 | 512 | 74.1 | 1 | ||
Birth defect | 0.0547** | ||||||
Yes | 8 | 20 | 69 | 9.7 | 2.19 | 1.04–4.57 | |
No | 32 | 80 | 641 | 90.3 | 1 | ||
Anemia | 0.0030 | ||||||
Yes | 2 | 5.3 | 174 | 26.9 | 0.16 | 0.04–0.66 | |
No | 36 | 94.7 | 473 | 73.1 | 1 | ||
Thrombocytopenia | 0.6474** | ||||||
Yes | 2 | 5.1 | 23 | 3.5 | 1.43 | 0.36–5.60 | |
No | 37 | 94.9 | 624 | 96.5 | 1 | ||
Hepatic changes | 0.0411 | ||||||
Yes | 19 | 51.4 | 101 | 34.2 | 1.86 | 1.02–3.41 | |
No | 18 | 48.6 | 194 | 65.8 | 1 | ||
TOTAL | 40 | 710 | |||||