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Fig. 3 | Reproductive Health

Fig. 3

From: Non-inferiority of cleavage-stage versus blastocyst-stage embryo transfer in poor prognosis IVF patients (PRECiSE trial): study protocol for a randomized controlled trial

Fig. 3

Possible outcomes of the PRECiSE non-inferiority RCT. The non-inferiority margin is set to a 10% absolute difference in live birth rate, which corresponds to a risk ratio (RR) of 0.6 for p.f.d 5 versus p.f.d.3 embryo transfer. a the lower bound of the confidence interval (CI) lies above the non-inferiority margin of 0.6: p.f.d. 5 is non-inferior to p.f.d. 3 embryo transfer (b) the lower bound of the CI lies above the non-inferiority margin and the CI includes the null value (RR = 1.0): p.f.d. 5 is non-inferior and equivalent to p.f.d. 3 embryo transfer (c) and (d) the CI includes the non-inferiority margin of 0.6: inconclusive (e) the upper bound of the CI lies below the non-inferiority margin of 0.6: p.f.d. 5 is inferior to p.f.d. 3 embryo transfer (f) the lower bound of the CI lies above the null value (RR = 1.0): p.f.d. 5 is superior to p.f.d. 3 embryo transfer

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Reproductive Health

ISSN: 1742-4755